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KMID : 0362719740120060419
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Journal of the Korean Dental Association
1974 Volume.12 No. 6 p.419 ~ p.423
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Baei Yu-Hong
Hahm Jhong-Dai
Lee Sang-Shin
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Abstract
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The authors have investigated the roles of cortisone and calcium on the depressive effects of local anesthetics on the acetylcholine-induced skeletal muscle contraction in frog. The results are as follows. 1. Tetracaine, cocaine, lidocaine and procaine decreased the acetylcholine-induced skeletal muscle contraction. 2. Cortisone increased the depressive effects of local anesthetics on the acetyl-choline-induced skeletal muscle contraction. 3. There was a tendency that in high calcium concentration, the depressive effects of cocaine and lidocaine on acetylcholine-induced skeletal muscle contraction were increased.
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